529. Overdiagnosis of Clostridioides difficile with a Multiplex PCR Panel
نویسندگان
چکیده
منابع مشابه
Detection of Virulence Genes of Clostridium difficile in Children with Cancer by Multiplex PCR
Introduction: Toxigenic Clostridium difficile is the major cause of antibiotic-associated diarrhea, colitis, and pseudomembranous colitis. The pathogenicity of C. difficile is related to toxins A&B. Children with cancer are at risk of developing C. difficile infection (CDI) due to increased exposure to antibiotics, immunosuppression, and longer hospital stays. Recently, due to higher sensitivity...
متن کاملdetection of virulence genes of clostridium difficile in children with cancer by multiplex pcr
introduction: toxigenic clostridium difficile is the major cause of antibiotic-associated diarrhea, colitis, and pseudomembranous colitis. the pathogenicity of c. difficile is related to toxins a&b.; children with cancer are at risk of developing c. difficile infection (cdi) due to increased exposure to antibiotics, immunosuppression, and longer hospital stays. recently, due to higher sensitivit...
متن کاملGut bacterial communities of diarrheic patients with indications of Clostridioides difficile infection
We present bacterial 16S rRNA gene datasets derived from stool samples of 44 patients with diarrhea indicative of a Clostridioides difficile infection. For 20 of these patients, C. difficile infection was confirmed by clinical evidence. Stool samples from patients originating from Germany, Ghana, and Indonesia were taken and subjected to DNA isolation. DNA isolations of stool samples from 35 as...
متن کاملClostridioides difficile Biology: Sporulation, Germination, and Corresponding Therapies for C. difficile Infection
Clostridioides difficile is a Gram-positive, spore-forming, toxin-producing anaerobe, and an important nosocomial pathogen. Due to the strictly anaerobic nature of the vegetative form, spores are the main morphotype of infection and transmission of the disease. Spore formation and their subsequent germination play critical roles in C. difficile infection (CDI) progress. Under suitable condition...
متن کاملToxin profiles and antimicrobial resistance patterns among toxigenic clinical isolates of Clostridioides (Clostridium) difficile
Objective(s): Clostridioides (Clostridium) difficile infection as a healthcare-associated infection can cause life-threatening infectious diarrhea in hospitalized patients. The aim of this study was to investigate the toxin profiles and antimicrobial resistance patterns of C. difficile isolates obtained from hospitalized patients in Shiraz, Iran.Mater...
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2018
ISSN: 2328-8957
DOI: 10.1093/ofid/ofy210.538